PVital PoleMedical
ED · PE · Low libido

Sex that works on your schedule,
not theirs.

Discreet, doctor-prescribed treatment for ED, premature ejaculation, and low libido. Shipped in plain packaging. From $2/dose.

Plain box · No name on label · No marketing on the package

Pick the fit

Four treatment paths for what's actually bothering you

Your clinician reviews your answers and picks the right one — you're never locked into a single option.

ED · On-demand

Sildenafil — take before the moment

Fast-acting PDE5 inhibitor for spontaneity. Take 30–60 minutes before intimacy; effective for roughly 4–6 hours.

  • Classic generic (same molecule as Viagra®)
  • Up to 6 hours of responsiveness
  • Food and alcohol can slow onset
Start ED assessment
ED · Daily

Tadalafil — always-on readiness

Low-dose daily option (or higher as-needed) that keeps you responsive for 24–36 hours without timing pills to sex.

  • Same-day or steady-state daily dosing
  • Up to 24–36 hours of responsiveness
  • May also improve BPH symptoms
Start ED assessment
PE · Topical

Lidocaine 4% — numb just enough

Applied 10–30 minutes before intercourse, topical lidocaine reduces glans sensitivity without affecting your erection.

  • Wash before sex to avoid partner numbness
  • No daily medication required
  • First-line in most PE guidelines
Start PE assessment
PE · Oral

Sertraline — daily SSRI (off-label)

A daily SSRI used off-label to delay climax. Typically helpful after one to two weeks of consistent dosing.

  • Best for lifelong or severe PE
  • Pairs well with topical lidocaine if needed
  • FDA boxed warning — clinician monitors mood
Start PE assessment
Women's libido · Topical

Arousal cream — local responsiveness

A compounded cream applied 15–30 minutes before intimacy to boost clitoral blood flow and sensitivity. It supports arousal, not desire.

  • Compounded — not an FDA-approved combo
  • Fast, localized, no daily pill
  • Wash before intercourse to avoid partner transfer
Ask about arousal cream
Connection · Nasal

Oxytocin spray — the bonding hormone

Compounded intranasal oxytocin used off-label to support a short-lived sense of connection, calm, and arousal before intimacy.

  • Used off-label — early evidence, individual response varies
  • Short-acting: 30–60 minute window
  • Avoid in pregnancy or while trying to conceive
Ask about oxytocin

Sexual wellness formulary

Real clinical data — no marketing fluff

Information paraphrased from MedlinePlus (NIH/NLM), FDA labels, and Cleveland Clinic. Always confirm with your clinician.

Sildenafil

aka Viagra®

As-needed PDE5 inhibitor — the classic generic option for ED.

How it works

Sildenafil blocks phosphodiesterase type 5 (PDE5), the enzyme that breaks down cGMP in penile tissue. With sexual stimulation, more cGMP means more blood flow and a firmer erection. It does not increase desire on its own.

Onset

Take 30–60 minutes before intimacy (up to 4 hours before).

Duration

Effective for roughly 4–6 hours. No more than one dose per 24 hours.

Common side effects

  • Headache
  • Facial flushing
  • Nasal congestion
  • Indigestion or heartburn
  • Blue-green color vision tint or light sensitivity

Don't use if…

  • Any nitrate medication (isosorbide, nitroglycerin) or nitrate-based recreational drugs (poppers)
  • Riociguat (Adempas)
  • Severe cardiovascular disease where sexual activity is inadvisable
  • Recent heart attack, stroke, or life-threatening arrhythmia

Tell your provider about…

  • Low or unstable blood pressure
  • Severe liver or kidney disease
  • Retinitis pigmentosa or prior NAION (sudden vision loss)
  • Bleeding disorders or active peptic ulcer
  • Peyronie's disease or penile deformity

Seek urgent care if you notice

Erection lasting longer than 4 hours (priapism) — seek care immediately
Sudden loss of vision or hearing
Chest pain, fainting, or irregular heartbeat during activity

Source: MedlinePlus — Sildenafil

Tadalafil

aka Cialis®

Long-acting PDE5 inhibitor — ideal for daily dosing and spontaneity.

How it works

Tadalafil is a PDE5 inhibitor like sildenafil but with a much longer half-life, enabling either low-dose daily use or higher as-needed dosing. With arousal, it increases blood flow to support a firm erection.

Onset

As-needed: at least 30 minutes before activity. Daily: steady state after about a week.

Duration

Up to 24–36 hours of responsiveness per dose, hence the 'weekend pill' nickname.

Common side effects

  • Headache
  • Indigestion, back or muscle pain (often delayed)
  • Facial flushing
  • Nasal congestion

Don't use if…

  • Nitrates in any form or recreational nitrates
  • Riociguat (Adempas)
  • Severe cardiovascular disease contraindicating sexual activity

Tell your provider about…

  • Alpha blockers for prostate or blood pressure (dose adjustments needed)
  • Severe liver or kidney disease
  • Benign prostatic hyperplasia (may also benefit)
  • Retinitis pigmentosa or prior NAION

Seek urgent care if you notice

Priapism (erection > 4 hours)
Sudden vision or hearing loss
Severe hypotension when combined with alpha blockers
Serious allergic reaction or skin blistering

Source: MedlinePlus — Tadalafil

Lidocaine 4% topical

Topical anesthetic that reduces penile sensitivity to help delay climax.

How it works

Lidocaine temporarily blocks sodium channels in surface nerves, dulling stimulation of the glans and shaft. Applied before intercourse, it can extend time-to-ejaculation without affecting erection quality.

Onset

Apply 10–30 minutes before intimacy.

Duration

Effect lasts roughly 30–60 minutes. Wash the area before intercourse to avoid transferring numbness to your partner.

Common side effects

  • Mild numbness or tingling at the site
  • Temporary reduced sensation
  • Occasional skin irritation

Don't use if…

  • Known allergy to amide-type local anesthetics
  • Broken or inflamed skin at the application site

Tell your provider about…

  • Use the smallest effective amount
  • Partner numbness — wash before intercourse or use a condom
  • Avoid contact with eyes and mouth

Seek urgent care if you notice

Severe allergic reaction (rash, swelling, trouble breathing)
Systemic absorption with large overuse — dizziness, irregular heartbeat

Source: Cleveland Clinic — Premature Ejaculation

Sertraline (off-label for PE)

aka Zoloft®

Daily SSRI used off-label to delay ejaculation in lifelong or distressing PE.

How it works

SSRIs raise synaptic serotonin, which — as a side effect — delays the ejaculatory reflex. Sertraline is one of several SSRIs (paroxetine, fluoxetine, escitalopram, citalopram) used off-label for PE, usually daily, sometimes 'on-demand' a few hours before sex.

Onset

Meaningful improvement usually after 1–2 weeks of daily dosing.

Duration

Taken once daily. Do not stop abruptly — taper under medical guidance.

Common side effects

  • Nausea or loose stools (first 1–2 weeks)
  • Headache
  • Decreased libido
  • Drowsiness or mild insomnia
  • Sweating

Don't use if…

  • Current MAO inhibitor use (within 14 days)
  • Pimozide use
  • Known hypersensitivity to sertraline

Tell your provider about…

  • Bipolar disorder or mania history
  • Seizure disorder
  • Bleeding disorders or anticoagulant use
  • Liver disease
  • Pregnancy or breastfeeding

Seek urgent care if you notice

Suicidal thoughts — especially in adults under 25
Serotonin syndrome when combined with other serotonergic drugs
Abnormal bleeding
Hyponatremia (low sodium)

FDA boxed warning

FDA boxed warning for all antidepressants: increased risk of suicidal thinking in children, adolescents, and young adults. Monitor closely for mood changes.

Source: Cleveland Clinic — Premature Ejaculation (SSRI off-label)

Viagra®

aka Viagra®

The original name-brand sildenafil — same molecule, branded manufacturing and blister packaging.

How it works

Viagra® is the brand name for sildenafil, a PDE5 inhibitor that increases cGMP in penile tissue so blood flow improves with arousal. Clinically equivalent to the generic; the difference is manufacturing, packaging, and price.

Onset

Take 30–60 minutes before intimacy (effective up to about 4 hours before).

Duration

Roughly 4–6 hours of responsiveness. One dose per 24 hours maximum.

Common side effects

  • Headache
  • Facial flushing
  • Nasal congestion
  • Indigestion or heartburn
  • Blue-green color vision tint

Don't use if…

  • Any nitrate medication or recreational nitrates (poppers)
  • Riociguat (Adempas)
  • Severe cardiovascular disease where sex is inadvisable
  • Recent heart attack, stroke, or life-threatening arrhythmia

Tell your provider about…

  • Low or unstable blood pressure
  • Severe liver or kidney disease
  • Retinitis pigmentosa or prior NAION (sudden vision loss)
  • Peyronie's disease or penile deformity

Seek urgent care if you notice

Erection lasting more than 4 hours (priapism) — seek care immediately
Sudden loss of vision or hearing
Chest pain, fainting, or irregular heartbeat during activity

Source: MedlinePlus — Sildenafil

Arousal cream (compounded)

Compounded topical applied before intimacy to boost clitoral blood flow and sensitivity.

How it works

A compounding pharmacy prepares the cream using vasodilators (commonly L-arginine and low-dose sildenafil) that relax local blood vessels. Applied to the clitoral area, it may increase blood flow, warmth, and responsiveness in about 15–30 minutes. It does not raise desire on its own.

Onset

Apply 15–30 minutes before intimacy.

Duration

Localized effect lasts roughly 30–60 minutes. Wash before intercourse to avoid partner transfer.

Common side effects

  • Mild warmth, tingling, or redness at the application site
  • Temporary increased sensitivity
  • Possible mild irritation

Don't use if…

  • Pregnancy or breastfeeding
  • Known allergy to any compounded ingredient
  • Broken, infected, or inflamed skin at the application site
  • Concurrent nitrate therapy (because the cream may contain sildenafil)

Tell your provider about…

  • Cardiovascular disease — discuss with your clinician
  • Use only the amount prescribed
  • Partner sensitivity — wash before intercourse or use a barrier

Seek urgent care if you notice

Allergic reaction — rash, swelling, trouble breathing
Systemic effects if overused or applied to broken skin

FDA boxed warning

This is a compounded preparation — not an FDA-approved combination product. Quality depends on the compounding pharmacy, and individual ingredients have their own warnings.

Source: FDA — Compounding and the FDA

Oxytocin nasal (compounded)

Compounded intranasal oxytocin used off-label to support connection and arousal.

How it works

Oxytocin is the bonding hormone released during intimacy and breastfeeding. As a compounded nasal spray it is absorbed through the nasal mucosa; some patients report a short-lived sense of connection, relaxation, and arousal when used before intimacy. Evidence is limited and use is off-label.

Onset

Typically 10–30 minutes after a spray in each nostril.

Duration

Short-acting — effects usually fade within 30–60 minutes.

Common side effects

  • Nasal irritation or runny nose
  • Mild headache
  • Facial flushing
  • Occasional nausea

Don't use if…

  • Pregnancy or actively trying to conceive
  • Known hypersensitivity to oxytocin
  • Severe cardiovascular disease

Tell your provider about…

  • Breastfeeding — discuss with your clinician
  • History of low sodium or kidney disease
  • Use only as directed — avoid dose stacking

Seek urgent care if you notice

Allergic reaction — hives, swelling, trouble breathing
Uterine contractions in pregnancy
Very low blood sodium (hyponatremia) with excessive use

FDA boxed warning

Compounded intranasal oxytocin is not FDA-approved for sexual wellness and is prescribed off-label. Evidence is early and individual response varies.

Source: NIH — Oxytocin overview

The Process

From assessment to refill
in clear steps

Backed by science

Proven molecules,
peer-reviewed trials

Weight loss · GLP-1

−22.5%avg body weightTirzepatide 15 mg · 72 wk
86%lost ≥ 5% body weightvs 32% on placebo

Sexual wellness

~70%ED response ratePDE5 inhibitors · RCTs
6–8×time-to-ejaculationTopical lidocaine vs placebo
01
1

Complete your health assessment

Tell us about your medical history, BMI, and goals. A US-licensed clinician reviews everything — most intakes are reviewed within 24 hours.

Takes ~3 minutes
02
2

Get your personalized prescription

If appropriate, your clinician prescribes a GLP-1 (semaglutide or tirzepatide) and the pharmacy ships in plain packaging.

Ships in 5–7 days
03
3

Adjust and stay supported

Free clinician messaging, dose adjustments, and coaching — so you're not just shipped a vial. Trial data: avg 15–21% body weight reduction at 68–72 weeks.

Ongoing care

Our Medical Team

Board-certified clinicians.
Named, with credentials.

MD

Medical Director

Internal Medicine · Obesity Medicine

RP

Lead Pharmacist

Compounding & dispensing oversight

CC

Lead Care Coach

Behavioral support · GLP-1 protocol

HIPAA Compliant

Your data is protected

Why Vital Pole

Medical care you can
actually trust

  • US-licensed clinicians
  • Most prescriptions reviewed within 24 hours
  • FDA-approved medications only, dispensed by partner pharmacies
  • HIPAA-secure intake & messaging
  • Unlimited clinician messaging
  • Same price at every dose — no surprise fees
  • HSA/FSA eligible program
  • Cancel in one click — no phone tree, no retention scripts
HIPAA Compliant
256-bit Encryption
FDA-Approved Meds Only
Board-Certified Physicians

FAQ

Real answers to real questions.

You complete a short health intake (about 3 minutes), a US-licensed clinician reviews everything you submit, and — if therapy is appropriate — a prescription is sent to a partner pharmacy that ships in plain packaging. You then message your care team anytime for dose adjustments, side-effect questions, or coaching. Cancel from your dashboard in one click.

Still have questions? Message our care team →

Now accepting new members

Get started in 3 minutes.
No card needed.

Physician-led care for metabolic weight loss and sexual wellness — same care team, one platform.

~3 minutes · No card needed · HSA/FSA eligible · Cancel anytime

FDA-approved

Medications only

US-licensed

Clinicians + pharmacies

1-click

Cancel anytime