PVital PoleMedical

The Process

From assessment to refill
in five clear steps.

No clinics. No phone tag. A US-licensed clinician reviews everything you submit before any medication ships.

See if I qualify

The Science

GLP-1: your gut's
natural appetite signal

GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in your gut after eating. It signals your brain to feel full, slows digestion, and regulates blood sugar. In people with obesity, this signal is often too weak.

GLP-1 receptor agonists — like semaglutide and tirzepatide — amplify this signal dramatically. The result: less hunger, slower digestion, improved metabolism, and significant, sustained weight loss.

🧠

Brain

Receives satiety signal → reduces appetite

⬇️
💉

GLP-1 Medication

Binds to receptors in gut, pancreas & brain

⬇️
🫀

Metabolism

Blood sugar regulated · Fat burning increased

2-4 lbs

lost per week on average

Consistent, gradual loss that your body can maintain.

15–20%

average total body weight lost

Clinical trial data across semaglutide and tirzepatide programs.

97%

report reduced food cravings

The appetite suppression effect is biological, not willpower.

STEP clinical trials (semaglutide)

Participants lost an average of 14.9% body weight vs. 2.4% with placebo over 68 weeks. Published in the New England Journal of Medicine, 2021.

Your Journey

What to expect, week by week

1
Week 1–2

Titration begins

  • Start at the lowest dose per FDA-labeled titration protocol
  • Mild nausea or fatigue can occur during dose increases
  • Appetite often begins to decrease
  • First check-in with your clinician
2
Week 3–4

Effects build

  • Many patients notice reduced food noise
  • Coaching session: protein-forward meals + strength training
  • Side-effect intensity typically eases between titrations
  • Message your care team anytime
3
Month 2–3

Finding your dose

  • Clinician may titrate upward if tolerated
  • Trial data: steady weight reduction continues through month 3
  • Adjust hydration and electrolytes as needed
  • Cravings often continue to decrease
4
Month 4–6

Real momentum

  • Per STEP-1 (semaglutide) and SURMOUNT-1 (tirzepatide), most loss accrues through month 6
  • Coaching focus: protect muscle mass while losing fat
  • Lab follow-up if your clinician recommends it
  • Plan for the maintenance phase together
5
Month 6–12+

Sustained results

  • STEP-1 reported avg ~15% body-weight loss at 68 wk; SURMOUNT-1 reported avg ~21% at 72 wk
  • Your individual response will vary
  • Maintenance protocol planning
  • Continued clinician access while on therapy

Platform

Everything you need in one place

App

Weight & progress tracking

Log weight 3x/week. Interactive charts show your trajectory with milestone badges.

App

Dose reminders

Smart reminders for weekly injections or daily pills. Never miss a dose.

Care

Direct provider messaging

Message your physician or coach anytime. Responses within 24 hours — often same day.

Care

Video coaching sessions

Bi-weekly 20-minute sessions with your dedicated health coach. Nutrition, habits, and accountability.

Safety

Side effect monitoring

Log symptoms in-app. Severity scores automatically alert your provider for follow-up.

Learn

Education curriculum

6 modules covering GLP-1 science, nutrition, exercise, plateau management, and long-term maintenance.

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Physician-led care for metabolic weight loss and sexual wellness — same care team, one platform.

~3 minutes · No card needed · HSA/FSA eligible · Cancel anytime

FDA-approved

Medications only

US-licensed

Clinicians + pharmacies

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